However, viewing asthma as a syndrome comprising different childhood wheeze phenotypes defined by distinct endotypes, including specific immunological patterns and environmental factors, is most likely more accurate [2, 5].
To achieve this 'high ground', rather than viewing asthma as a series of acute events, it is important to take a life-course view initially focusing on young children and the early-life factors that drive the origins of the disease, and then to track the structural changes and functional airway responses through childhood, adolescence and into adults.
The view that asthma is primarily an allergic disease mediated by Th2 cytokines has been challenged because asthma can develop in the absence of atopy.
Similarly, few previously identified facilitators, such as parents' positive view of asthma, [ 45] were not brought up by our patients.
All were clinicians working in primary care or paediatric pulmonology, who have seen many preschool children with wheeze, and whose individual views on asthma phenotypes were not previously known to the core group.
To understand how Medicaid recipients with asthma view their experience with care.
From a medical point of view, obesity, like asthma, is something that happens to a person — a disease with many etiologies, not all of them well understood.
Nevertheless, even school district level prevalence estimates offer a more comprehensive view of pediatric asthma prevalence on the local level than do other surveillance data currently available.
Changing from 'no more than two' to 'three' inhalers had the highest relative negative impact on respondents' views of their asthma management.
Our observations support the view that atopy and asthma, although strongly linked, are distinct components of the asthma syndrome, each with their own pattern of risk or protective factors (Von Mutius 2001).
