We attribute the influence of Pt to the spillover of dissociated oxygen atoms from Pt to the vicinal Ba sites.
In a formal sense, a carbene such as 9 can be thought of as being derived from an alkyne substrate that has reacted as a species with 1,2-dicarbene character: One of the vicinal carbene sites gets trapped by the ruthenium fragment, whereas the other one oxidatively inserts into the H H bond of the reagent (Scheme 1).
The PTP1B catalytic site and vicinal non-catalytic site are surface-exposed, highly hydrophilic, and recognize charged phosphotyrosine (pTyr) residue or pTyr mimetics (Figure 4A).
It was suggested that furfuryl alcohol is formed through dehydration-hydrogenation cascade reactions on independent acid and metal sites on dual catalytic systems while one-step conversion occurs on vicinal acid-metal pair sites created on single multifunctional catalysts.
Glutaredoxin contains vicinal dithiols in the catalytic site and its function is usually characterized in vitro using purified S-glutathionylated proteins.
The thioredoxin-1 (Trx-1) isoform of Trx, the main intracellular antioxidant oxidoreductase [ 8- 10], is normally in its reduced state (Trx-1- SH 2), Trx-1- SH 2marily by two vicinal cysteine thiol groups at its active site (Cys32 andefined).
In brief, the leaf discs collected from the vicinal regions with equivalent distance from the inoculated sites were cultured in Tris buffer (10 mM Tris, 50 mM KCl, pH 6.1), followed by incubation in a loading buffer (10 mM Tris, 50 mM KCl, pH 7.2) containing 50 μM of H2DCF-DA for 20 min in dark.
In addition to the identified candidate nsSNPs for increased or reduced arsenic responsiveness, we observed i) a nsSNP that results in the breakage of a disulfide bond, as candidate marker for reduced arsenic responsiveness of KLK7, a secreted serine protease participate in normal shedding of the skin; and ii) 6 pairs of vicinal cysteines in KLK7 protein that could be binding sites for arsenic.
The high activity of both catalysts is related to vicinal silanol groups and silanol nests with weak acidity and negligible Brønsted acid sites.
Vicinal cysteines are rather rare in proteins, the more if found near the N-terminus distant from the active site of the enzyme.
Combined with SEM/EDS system observation, it was found that for solution-annealed specimens, sulphide and oxide mixed inclusions were the preferential pit initiation sites, while for aged specimens, majority pits occurred at inclusions in area impoverished in Cr/Mo, which is vicinal to σ phase.
