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In this polymer, the boronic acid moiety binds compounds containing vicinal diol moieties with high affinity through reversible esterification.
Sulfhydryl groups of vicinal or closely spaced cysteines are typical high-affinity targets for trivalent arsenicals in protein structures (Altamirano et al. 1989; Carlson et al. 1978; Chakraborti et al. 1992; Delnomdedieu et al. 1993; Li et al. 2001; Lopez et al. 1990).
Adequate cysteine content and vicinal cysteine residues were shown to be required for high-affinity arsenite binding with the peptides.
Kalef et al. prepared affinity resins based on Sepharose 4B linked with aminohexanoyl-4-aminophenylarsine oxide to purify proteins containing vicinal dithiols from L1210 murine leukemia lymphoblasts.
Extensive structure activity studies suggest that the vicinal 4,5-bisphosphate structure of IP3 is essential, while the 1-phosphate has an ancillary role that substantially increases affinity.
Affinity indeed.
Affinity suffices.
Chromatography, Affinity.
Cultural affinity supercharges communication.
In Si 553 -Au and related vicinal Si 553 -Aurfands, this anisotrelatedises naturally at the step edge.
Visinoiu, A. et al. Initial growth stages of epitaxial BaTiO3 films on vicinal SrTiO3 (001) substrate surfaces.
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