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FLT3 inhibitors have been explored as a viable therapy for acute myeloid leukemia (AML).
Preclinical investigations and early clinical trial studies suggest that FLT3 inhibitors offer a viable therapy for acute myeloid leukemia.
Recent results showing clinical evidence of efficacy using immunotherapy in other types of tumors, such as melanoma and lung cancer, have also made this a viable therapy for evaluation in colorectal cancer in clinical trials.
Recently, a patient was successfully transplanted with allogeneic, naturally resistant CCR5-negative (CCR5Δ32) cells, setting the stage for transplantation of naturally resistant, or genetically modified stem cells as a viable therapy for AIDS.
Collectively, these data suggest that activated rac can directly promote a fibrogenic phenotype through PI3kinase/Akt and that targeting rac may be a viable therapy for fibrosis, including that observed in SSc.
We propose that an active lifestyle is an important determinant of quality of life and molecular progression of aging in skeletal muscle of the elderly, and is a viable therapy for attenuating and/or reversing skeletal muscle strength declines and mitochondrial abnormalities associated with aging.
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Further research examining interoceptive awareness may also prove fruitful in identifying relevant factors and viable therapy targets for improving sexual functioning in women and in men.
Exercise may also represent a viable therapy in patients for whom pharmacological treatment is unavailable, ineffective, or inappropriate.
We suggest that pharmacologic modulation of neutrophils should be explored as a viable future therapy for severe RSV-induced bronchiolitis and thereby prevent the inception of subsequent asthma.
Therefore, gastric bypass surgery may be a viable surgical therapy for treating T2D.
These findings indicate that cooling could represent a viable neuroprotective therapy for AD-HSP and potentially other neurodegenerative disorders.
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