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These data suggest that HITS monitoring is not a viable surrogate marker for increased thromboembolic risk in such patients with DCM.
The clinical impact of the SIRRIM technique could be considerable, considering that it might become a viable surrogate to other techniques.
Results of the RFT-based hydrodynamic model are compared against further CFD simulations, and indicate that the model with hydrodynamic interaction coefficients obtained from a representative design provides a viable surrogate for computationally intensive three-dimensional time-dependent CFD models for a range of design variables.
Reduction in reactivity is a viable surrogate of reduced thrombogenic milieu [ 15].
A multidisciplinary strategy is addressed to the development and creation of viable surrogate tissues for a prospective replacement of malfunctioning valves.
The study also demonstrated that the CDR is a viable surrogate for assessing nuclear size, and that digital imaging may detect prognostic information not be readily apparent by visual inspection.
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We have demonstrated that MLST, as a nucleotide sequenced-based strain typing method, has the power to bring life to a microbial metagenome by the identification of matching cultivable clones, which may now be used as viable surrogates for research using the metagenome.
In addition, since the study of the Burkholderia genus is one of our primary interests, the matching cultivable strains also brought the opportunity to bring life to a hypothetical metagenome, which without viable surrogates was of limited practical use to our research community.
Therefore, the critical need guiding drug development for NAFLD/NASH is to identify viable surrogates that are predictive of those outcomes.
However, up to 50% of expression changes in leukocytes for highly heritable cis-acting traits are also mirrored in other tissues such as adipose tissue, making them viable surrogates for exposure of other tissues (Emilsson et al. 2008).
This will help to develop clinically viable early surrogate biomarkers of AD pathology in prodromal individuals.
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