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He outlined plans for a new slimmed down AIB structure with a new customer-focused "viable core" of retail and business banking that would be half the size of the existing operation by 2013.
In the end, after further poking and prodding by our faculty coach, we delivered a comprehensive market and gap analysis, four viable core business models for the German market and a project plan outline for other things the company would need to do before entering it.
Previous efforts by our group have established pyrazolo[1,5-a]pyrimidine as a viable core for the development of potent and selective CDK inhibitors.
'Mutation' happens either when uncatalyzed reactions result in the emergence of a novel core, or when molecular components of a viable core are stochastically lost after compartment splitting.
Note that although the number of viable loops increases with system size, they are always within the same viable core and therefore they cannot be independent targets for natural selection (see Additional file 1).
The reason for the selectability in this model is that a novel viable core results in a new and distinct attractor for the reaction network, and due to its autocatalytic properties enables a higher (non-food mass) growth rate.
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We conclude that only when a chemical reaction network consists of many such viable cores, can it be evolvable.
These conditions are the existence of rare reactions producing viable cores (analogous to a genotype), that sustains a molecular periphery (analogous to a phenotype).
Whenever novel spontaneous reactions occur, the number of possible uncatalyzed reactions also increases, opening up new possibilities for discovering viable cores (genotypes) and their corresponding peripheries (phenotypes).
However, these facts merely change the probability of formation of viable cores in particular chemical systems, not the fact that Darwinian evolution is possible once they appear.
Scores were totalled across the three cores; cases with only one core present were excluded, cases with two viable scores had the third missing score replaced with the mean of the two viable cores.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com