Sentence examples for viable compounds from inspiring English sources

"Big data allows us to cast a wide net initially to identify leads, while 'big knowledge' allows us to quickly select viable compounds to test," Webb says.

Calling the experiment an "intelligent approach," neuroscientist Michael Weiss of the University of Washington, Seattle, says he's impressed that team combed through so many FDA approved drugs and managed to hit on a "viable compound".

To minimize possible compensatory effects, B-rafΔ8b/Δ8b and B-rafΔ9b/Δ9b animals were further crossed to B-raf -/+ C-raf -/+ viable compound knockout mice [7].

Taken together, the present findings indicate that these curcumin analogs are viable lead compounds for the development of new central and peripheral nervous system cancer chemotherapeutics with the potential for little effects on normal hematopoietic progenitor cells.

Structural evidence helps explain the need for covalent inhibitors and the lack of pharmacologically viable lead compounds.

Once the HD field homes in on viable lead compounds, HD-iPSC models could serve as invaluable tools for validation and should accelerate therapeutic development.

Direct NMR-based screening of large libraries of peptide mimetics as in HTS by NMR may provide viable hit compounds for more immediate hit-to-lead optimizations.

Based on these results, 3-MeSO2-DDE remains a viable lead compound for drug design, although the adrenocorticolytic effects of 3-MeSO2-DDE in human cells seem more complex than in murine cells.

Jnk1−/− mice and Jnk2−/− mice are viable, but compound mutant Jnk1−/− Jnk2−/− mice exhibit an early embryonic lethal phenotype [1].

The data presented here increase our knowledge about the protective and beneficial mechanisms of SG for menopausal symptoms, and it may therefore be a viable candidate compound for the development of therapeutic drugs for the management of menopausal symptoms.

Compensating factors are likely to be other Sp-family members such as Sp3 as indicated by the finding that mice heterozygous for either Sp1 or Sp3 are viable, but compound heterozygous are not (Kruger et al., 2007).