Sentence examples for viability of compounds from inspiring English sources

Part of the reason for this is that the drug manufacturers are concerned over the viability of compounds for commercial sale and use.

The cell viability of these compounds was quantified by MTT assay.

Because the effects on cell viability of all compounds were previously evaluated to ensure that the HCV inhibition was not due to cytotoxicity, it is not surprising that no significant cytotoxicity was observed with the combination of PBZ or either of the other compounds (Fig. 5).

Some limitations remain, however, such as the risk to induce unwanted physiological responses triggered by the same type of interactions (or loss of interaction), or the clinical viability of these compounds in terms of toxicity, body clearance or administration.

In preclinical stages, models serve to assess the viability of candidate compounds, combining data derived in vitro with in vivo preclinical species (i.e., rat) data to provide estimates of human PK.

Both compounds (261, 262) exhibited significant effects on the growth and viability of cells, compound (261) shows moderate cytotoxicity inhibition against human breast cancer cells (IC50 44.5 µM).

Hela, Supt1 cancer cell lines were used to evaluate the impact on cell viability of each compound.

This is a challenge magnified by the low viability of the compound mutants.

Similarly, using the hPXR DPX-2 agonist assay, we found generally good agreement with the hPXR HepG2 data, although Z,E-fenpyroximate appeared to be a weak hPXR agonist; the cell viability of this compound suggests it is also cytotoxic [median inhibitory concentration (IC50), 0.04; Table 2].

The economic viability of using such compounds is however pending to the releasable hydrogen content as the maximum value is only about 7.2wt%.

The cell viability of all tested compounds after 15 h incubation time is displayed in Figure 4.