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Taken together, these data suggest that RhoH regulates TCR signaling via recruiting ZAP-70 and Lck to CD3ζ in the immunological synapse for activation of downstream signaling molecules.
The number of Bcl11b-regulated genes was recently extended to include the major cell cycle regulator and tumor suppressor CDKN1A/p21WAF1 which was demonstrated to be repressed by Bcl11b acting via recruiting histone deacetylases and methyltransferases to the p21WAF1 promoter [13].
It can silence the gene expression via recruiting mSin3A/B and CoREST [ 124, 125].
The 15Rαβγ complex signals via recruiting Janus kinase (JAK) 1/3 to the β – and γ-chain receptors, respectively.
However, over-expression of XIST may alter epigenetic state of inactive X chromosome via recruiting excessive XIST-dependent protein complexes.
If MeCP2 functions to facilitate ASE inclusion via recruiting HDAC activity, knockdown of MeCP2 may lead to increased histone acetylation at the affected ASEs.
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It has been proposed that TJs may decrease the activity of these pathways most probably via recruited proteins.
For activation of NF- κB, TNF α via TNFR1 recruits TRADD, TRAF2 and RIP.
Recruiting donors via cold calling has become standard practice.
They were recruited via an online recruitment system.
Participants were mostly recruited via post (89%) or via their general practitioner's surgery.
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