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These compounds seem to affect neuroprotection via pathways independent of the classical estrogen receptors.
Nicks undergo efficient repair by single-stranded oligonucleotide donors complementary to either the nicked or intact DNA strand, via pathways that are normally suppressed by RAD51.
Dysplasia and colorectal cancer (CRC) in ulcerative colitis (UC) develop via pathways distinct from sporadic CRC and may occur in flat mucosa indistinct from surrounding tissue.
The cytokine MIF is involved in inflammation and cell proliferation via pathways initiated by its binding to the transmembrane receptor CD74.
The undesired uptake of these toxic species is possible via pathways designed for the uptake of other structurally and chemically similar essential compounds.
The results of the present study suggest that neuronal ET-1 is involved in endogenous pain inhibitory control likely via pathways through the hypothalamus.
Synthesis of propionate from CO2 has been observed previously, via pathways speculated to include a reversal of syntrophic propionate degradation or reductive formation from H2 + CO2 in combination with homoacetogenesis (Conrad and Klose [1999]).
Mesp2 suppressed itself through a feedback loop and suppressed Notch activity by destabilizing Mastermind-like 1 (MamL1), one of the core components of the nuclear NICD complex, at the post-transcriptional level via pathways other than the proteasome pathway (Sasaki et al., 2011).
For example, depolarization triggered by glucose metabolism opens L-type voltage-gated Ca2+ channels, leading to an initial extracellular Ca2+ influx (Rorsman 1997) and the subsequent mobilization of Ca2+ stores via pathways such as the IP3 and ryanodine receptors (Islam 2002; Duman et al. 2006).
This suggests that CSPG may enhance STAT3 signaling via pathways besides EGFR.
Our main result is that cannabinoids exert their effects on feeding via pathways that are independent of the melanocortin system.
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