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Curcumin was reported to inhibit P-12-LOX via binding to its active site [28, 29].
Curcumin was reported to inhibit this enzyme via binding to its active site.
The down-regulation by E2 predominantly arose via binding to nuclear ERs.
c-Jun regulates the responsive promoter via binding to its canonical TGAG/CTCA motif (AP1) (Angel et al., 1987).
We demonstrated that CDK6 can be downregulated by miR-29b via binding to the 3′-UTR region in osteosarcoma cells.
BA sequestrants such as non-absorbed resins lower BA levels via binding and removing them from enterohepatic circulation [16].
The hypoxia-inducible factor (HIF) activates transcription via binding to the highly variable hypoxia-responsive elements (HREs).
Oligonucleotides investigated include phosphorothioates that cleave their target and vivo-morpholinos that modulate target RNA activity via binding.
Prostate cancer cells secrete PSA locally that is proteolytically active; however, circulating PSA is inactivated via binding to protease inhibitors.
This might reflect inhibitory effects exerted by the Fc part via binding to FCGR2.
Hexokinase (I and II) is associated with the mitochondrial outer membrane via binding to porin [61].
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