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The great vessel space surrounds the aorta and the inferior vena cava (IVC) and is anterior to the vertebral bodies and psoas muscles.
In both groups of mice, bacteria could be sporadically found within the vessel space (Fig. 5f,g).
Myometrial invasion to the outer half was reported in 10 cases, cervical stromal invasion in 4 cases and lymph vessel space involvement in 8 cases.
LBVIH&E was identified using criteria previously described [ 6], as the presence of tumour cell emboli within a vessel space, which were identified by associated fibrin clot and/or an endothelial cell lining.
Similar(56)
Compression is commonly due to a blood clot inside the brain or formed outside or beneath the dura mater (extra- or subdural hematoma), but inherent swelling of the brain tissue following trauma is also possible as fluid leaks from small blood vessel spaces into the extravascular space (brain edema).
The retroperitoneum is loosely divided into the anterior and posterior pararenal, perirenal and great vessel spaces.
Typical vascular abnormalities include vessel tortuosity, abnormal vessel spacing and branching, vessel leakiness, and failed integration of vascular networks resulting in numerous blind ends (reviewed in [2], [3]).
Robust angiogenesis in the overlying dermis is typically evident by four days, and the neovasculature routinely exhibits all of the hallmarks of pathological angiogenesis (e.g., vessel tortuosity, abnormal vessel spacing and branching, vessel leakiness, and failed integration of vascular networks resulting in numerous blind ends).
Consistent with this finding vessel surface and vessel number were increased, whereas vessel spacing was decreased in arthritis.
Using a combination of immunohistochemistry and image analysis techniques, four pathophysiological indices were determined: (1) total vessel spacing, (2) perfused vessel spacing, (3) % vascular area, and (4) overall tumour hypoxia.
Although neither perfused vessel spacing nor tumour hypoxia was significantly altered in the VEGF165 tumours, VEGF121 tumours demonstrated significant changes in both.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com