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Concerning angiogenesis, it has been reported that activation of Shh cascade evoked in vitro capillary-like structures formation and in vivo new blood vessel generation [10] [12].
Subnetwork B showed some key pathways of blood vessel generation.
D* was significantly increased, which likely reflects the increased blood vessel generation and parenchymal perfusion in patients with primary NPC.
Angiogenesis, the process of new blood vessel generation from capillary or post-capillary venules, requires gross changes in endothelial cell function.
D was significantly decreased in primary NPC, and increased D* reflected increased blood vessel generation and parenchymal perfusion in primary NPC.
High VEGF levels can promote plasma protein exosmosis to induce fibrin deposition and new vessel generation, allowing invasion and metastasis; patients with HCC and higher VEFG expression in serum and HCC tissue have a poorer prognosis [ 9, 26].
Similar(52)
VEGF is upregulated by hypoxia (Shweiki et al, 1992), and by overexpression of oncogenes such as mutant ras (Rak et al, 1995) and c-myc (Mezquita et al, 2005) in tumours, and stimulates the migration of endothelial cells, sprouting of blood vessels, and generation of new vessels from existing vasculature in tumours (reviewed in Ferrara, 2004).
Dilation affects the structure of the flow and, in turn, altered flow may play a role in vessel dilation, generation of aneurysms, and dissection.
MRA showed vessels from a number of different generations starting with the cotelydonary arteries branching off into primary, secondary and tertiary stem vessels: even 6th generation blood vessels were visible.
Their proposed system consists of blood vessel segmentation, feature generation, and feature matching parts.
This system comprises of three principal modules including blood vessel segmentation, feature generation, and feature matching.
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