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There are therefore very substantial variations in medical, nursing and couch-time resource implications for patients receiving systemic therapy, which are not fully identified in our audit.
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Unexpectedly, we found very substantial variation in map distances in two wild-type ARC haplotypes relative to the size reported for our congenic line.
Very substantial variation of biomass accumulation and metabolite composition has recently been observed across A. thaliana accessions [ 21- 23] suggesting that local adaptation involves changes in metabolic traits that may result from natural selection.
The results of the present work suggests that such national shapes and trends in notifications data can be quite robust to very substantial variation in under-reporting between regions.
This helps us to avoid the health states reflecting idiosyncratic variation, which can be very substantial in metastatic disease.
However, the fact that most of the adjusted rates showed differences that were very small implies that there were likely no substantial variations in quality of care between these two regions.
The observational evidence of the human health impacts of variations in climate conditions is now very substantial, particularly in relation to heat and cold exposure (10, 17).
Average observed and predicted rates were very similar, but the variation in rates was higher for the observed rates compared with the predicted rates, suggesting substantial variations in excess mortality and quality across the sample.
Very substantial?
Impulse, and very substantial technique.
He's very substantial".
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