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Indeed, the desmethyl urea lipids in particular exhibited very strong activity against Leishmania donovani and were in fact at least 10 times more active than the methylated derivatives (Table S2).
Our results also show that compounds 5e and 5i have very strong activity against MCF-7 and HCT116 with IC50 values of 3.02 4.13 μg/ml.
10.01am GMT ING: UK could achieve 3% growth in 2014 Reaction is flooding in: ING's James Knightley reckons that the UK could grow by up to 3% in 2014: With business surveys, such as the purchasing managers' indices and the British Chambers of Commerce reports indicating very strong activity across the economy it looks as though there is significant momentum at the beginning of 2014.
This experiment showed a very strong activity of two extracts against colon cancer cells.
This experiment declared a very strong activity of two extracts against breast cancer cells.
In our study, the crude methanol extract of T. conoides exhibited very strong activity against S. pneumoniae, S. aureus, and B. cereus.
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Within the collection of biopsies analysed, DNA-binding activities of STAT1/3 homo- and heterodimer complexes ranged widely from very strong activities to no significant detection of STAT1/3 activity (in two samples, number 14 and number 18).
We found that the very strong gelatinolytic activity of activated satellite cells/myoblasts occurring upon exercise reflects the presence of MMP-9, but not MMP-2 (Fig. 4h n).
The leaves infiltrated with 1391Z had no GUS activity while the leaves infiltrated with P35S had a very strong GUS activity (see additional file 2E, F).
On the other hand, there were few focal accumulations of cells expressing Pax-7 or MyoD (a marker of activated satellite cells and myoblasts) that had very strong gelatinolytic activity in their cytoplasm (Fig. 4e g); the cells lied within the apparent remnants of necrotic myofibers, but did not express a pan-leukocyte marker CD45 (Fig. 4o r).
Among a group of recently described antimicrobial peptides that are produced by human epithelial cells, S100A7/psoriasin exhibits very strong antimicrobial activity at low molecular concentrations [ 14], which was confirmed by comparing the activity of natural N-acetylated S100A7/psoriasin with that of chemically synthesized N-acetylated S100A7 [ 15].
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