At this time, most methods tend to assume very simplistic scenarios to account for variation in population size through time, 56 but development of methods accounting for more complicated underlying demographics is ongoing.
As a very simplistic method to account for this we chose to examine how the number of rotational bonds in the ligand would influence the predicted binding free energy.
Pride, ego, and an unwillingness to see the larger picture caused a very simplistic decision to turn into a debate that lasted much longer than it should and took them away from the single most important task at hand... fixing the car.
Here, we first derive mathematically a linear model for this relationship under very simplistic conditions (to be outlined), and this model is subsequently generalized to encompass a large and more realistic range of relationships.
I always thought part of the problem was a very simplistic approach to the issue; there was this anti-drug trade propaganda in Colombia similar to Nancy Reagan's "just say no" campaign.
"The income rules are a very simplistic way to solve what is quite a small problem of people abusing the rules," she said.
"The notion of putting a police officer in every school no matter what is a very simplistic answer to a complex issue," said Mr. Woods, whose district is the state's fourth largest, with about 94,000 students.
This, of course, is a very simplistic way to look at these things – the truth is that for Groupon, like many companies, Facebook could prove to be a phenomenal platform for massive user acquisition.
Of course, this is a very simplistic approach to satiety and enjoyment of food; complexity is at best just one of many factors affecting our appreciation of the food we eat.
