Sentence examples for very significant shift from inspiring English sources

"This year we have noticed a very significant shift in student progression," says Professor Peter Carolin.

"There is now a very significant shift toward corporations endeavoring to be far more transparent on what they are doing," Mr. Greenspan said.

"I think it's a very significant shift," said Urvashi Butalia, publisher of Zubaan Books, based in New Delhi, which promotes women's writing.

"It's a very significant shift," said Gopal Ahluwalia, an economist and vice president of research at the National Association of Home Builders.

"For families to accept that women will remain single, that they will live on their own, that they will work and defer marriage, is a very, very significant shift," she said.

It may be too early to proclaim an end to the "Cheney era", but Washington's decision to participate in Saturday's nuclear talks with Iran and send diplomats back to Tehran is a very significant shift.

I've counted at least 11 very significant shifts in the Lib Dem front bench's position on the economy in two years, most of which aren't actual party policy.

The man who used to be charge of the Civil Service, Lord Gus O'Donnell, who was so instrumental in putting together the coalition in 2010 thinks it is, and that there are two very significant shifts that makes this election very significant, and potentially very messy.

Similarly, R137C and R137L receptors presented a weak sensitivity to AVP stimulation, compared to the wild-type receptor, dose-response curves with R137C and R137L mutants exhibiting a very significant rightward shift of AVP potency and a lower efficiency (Figure 1b and Table 1).

Both diclofenac and tetra-ethyl-ammonium (TEA) pretreatment of GPAPs induced a suppression of the relaxation caused by ESera, and produced a very significant rightward shifts of the CRC (16-fold) for diclofenac and increase the Emax.

This modest chemical change results in a very significant and unexpected shift in the selectivity of COX inhibition, creating a molecule that is a highly potent, slow, tight-binding inhibitor of COX-2 lacking significant COX-1 inhibitory activity.