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"The result is very significant if it turns out to be robust," he said.
If the balls swing – a very significant if – this quartet can take wickets in bundles.
All of which could make an overwhelmingly pro-Brexit press very significant if the polls are close.
It may not happen but the risk to our economy is very significant if we are not prepared".
"I think Witness 8 is a very significant, if not the most significant, witness," Mr. O'Mara said.
When famous men embrace feminism, the public adoration becomes even more feverish because, my goodness, it must mean something so very significant if a man is supportive of gender equality.
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The measurement of solids is a very significant parameter if the water is being used for drinking purposes.
With an estimated 18% of the web browser market, the data would be very significant even if only a small fraction of Firefox users choose to participate.
Mr Modi's government is already attempting to replace the network of state taxes, a huge barrier to trade within the country, with a national goods and services tax - a very significant reform, if he can only get it passed.
In light of all these, this recent decision by the Obama administration is very significant, only if the President will also follow through with denying Shell the permit to drill in the same polar bear habitat that he just designated.
The secondary effects, cholangitis and liver abscesses can be very significant, particularly if the patient requires chemotherapy at some later date.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com