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The ability to find the right relationship at the first try, or, if the computer made one of its very rare errors, to rectify that without any financial or emotional loss.
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A very rare type of error is homozygous reversal, which means a shift from one homozygous genotype to another (e.g. AA → BB).
Another problem is the measurement accuracy: since genotype calling is based on fluorescent intensity and clustering, it will be hard to distinguish very rare variants from genotyping errors.
Using simulated and real data we have ascertained that this type of error is very rare with our method (unpublished data).
Since diagnosing seroprevalence is less error prone than correctly assessing the very rare event of acute infection, this method was robust against diagnostic errors.
In fact for high SNRs, the wrapped phases are unwrapped correctly because the errors multiple of ±2π become very rare.
Given that having an error on both SNPs of an LD pair would be a very rare event and further given that if there is an error on both SNPs it is not likely it would be the same type of error for systematic reasons, this simplification shouldn't bias our estimate of error rate very much.
The inclusion of very rare cancers with unstable survival estimates introduces random error into the current analysis, which could obscure a genuine pattern.
In wireless networks, congestion is very rare, and frequent RTOs are often due to transmission errors [3].
This may result from an error in the recorded pedigree, from genotyping errors, or from mixing up DNA samples and in very rare cases from mutations.
In studies with a high depth of coverage it is the sequencing error rate (both sequencing and PCR errors) that is the limiting factor in the identification of very rare variants.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com