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It would take very few alterations to turn "Hora" into a study of institutionalized psychosis.
As each chapter was finished, it was sent off to New York, and that typescript, with very few alterations, became the final text of the novel.
If you've seen OK Go's music video for their song "Skyscrapers," then you've essentially seen the second premiere, also called Skyscrapers: Sie, who choreographed and performed in the video, set its choreography on Pilobolus (assisted by Paula Salhany and Jaworski) with what seems like very few alterations.
However, about 25% of the "high-risk" tumors had very few alterations.
Twelve tumors are classified in the third cluster (gray in Figure 4) characterized by no or very few alterations.
Transcriptional profiling studies using whole brain from Mecp2-null mice revealed only subtle gene expression changes (22), and studies investigating cerebellar gene expression changes identified very few alterations that did not withstand a correction for false discovery rate (FDR) (23).
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However, embryos singly injected either with the human NLSmut- or LC8mut-Pak1 mRNA showed very few morphological alterations, consistent with the view that deleterious effects of Pak1 overexpression on zebrafish morphology and survival depend on nuclear import (Figs. 5A and B).
These damages were present up to 12 h after stress, whereas at later time points post stress, no or very few histological alterations could be observed [ 27].
Remarkably stage 4+ disease appears to have very few genomic alterations when compared with Stage 1 and 4- implying that MYCN amplification is sufficient to drive these tumors to an aggressive phenotype, and although other genomic changes occur, including loss of 1p36 as shown by us and others [ 40], it does not require extensive changes.
Very few significant alterations in the expression of features on the microarray were observed after exposure of J2315 to amikacin (19 of 8740 probes; Table 2), while exposure to meropenem and trimethoprim-sulfamethoxazole resulted in approximately three times this number of features altering in expression (Table 2).
However, non-severe SAH (WFNS 1 to 2) was used as comparator because the levels of catecholamines in these patients were within the normal range (<2,500 pmoles/L and <500 pmoles/L for epinephrine and norepinephrine, respectively) and they had very few cardiac alterations.
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CEO of Professional Science Editing for Scientists @ prosciediting.com