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"It was very difficult to settle down".
But he found it very difficult to settle.
Unfortunately, the data sources are bad enough that it will be very difficult to settle this argument conclusively.
Cytogenetic abnormalities and gene alterations in tumors co-occur with other abnormalities, and the complex state of molecular abnormalities in tumors makes it very difficult to settle on a set of alterations characteristic of classes of tumors.
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But on the pitch used for Thursday's opening match of the tournament between India and South Africa they found it difficult to settle from the very first delivery when Brendon McCullum leaped full length high to his left at slip to grab Kusal Perera's edge.
Shareholders who try to support such broader interests can find it very difficult to oppose settled corporate policies and simply turn to invest elsewhere.
It's surprisingly difficult to settle on an answer.
That issue will be much more difficult to settle.
It is difficult to settle on a single definition and formalism of trust.
Those in opposition mount three kinds of claims: (C1) In much of medicine, and especially psychiatry, we do not know with any certainty what is evolutionarily natural, because our scientific studies are still in their early stages or highly programmatic, and it can be very difficult to find data that will settle scientific controversies.
The warmth of a tungsten bulb or flame illuminating a creamy page and ink-black (naturally) text is very difficult to replicate, and at the time they had to settle for something quite a bit colder, color-wise.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com