Sentence examples for very difficult to design from inspiring English sources

It's very difficult to design block grants that would respond as nimbly to economic swings.

The complex shapes required to reduce the boom proved to be very difficult to design by hand.

It is very difficult to design an optimal hp mesh by hand.

However, such complex models are very difficult to design and analyse.

This makes it very difficult to design and manufacture a satisfactory structure using these models.

Due to lack of hydrological data and the area's extreme floods, however, it is very difficult to design the overflow weirs.

Very wideband amplifiers were difficult to design and build until the advent of monolithic microwave integrated circuit (MMIC) devices.

Because these two paralogues are very similar, it was difficult to design gene-specific primer pairs for the coding region.

Animal models have been difficult to develop and very costly, while clinical trials are difficult to design and perform in ACHD, leaving gaps in our understanding of the pathophysiology and treatment of congenital heart disease.

The ligand-binding pockets of all serotonin receptors are very similar and, therefore, it is difficult to design an inhibitor exhibiting high degree of specificity for a particular serotonin receptor.

This makes it very difficult to perform design calculations and to analyse the normal and abnormal behaviour of nuclear installations where these coolants are expected to be used.