Sentence examples for very close linkage from inspiring English sources

We think pleiotropy is unlikely for the variants that we used to generate the CRP haplotypes as they are in very close linkage disequilibrium with variation within a putative transcription factor binding site located 5' of the CRP gene that has been associated with circulating concentrations of CRP and thought to be functional [43], [44].

One might also conjecture that ligands and receptors might at times need to be co-expressed [see e.g. [ 31]], so very close linkage might be beneficial for this reason as well.

For markers which are in very close genetic linkage, as these are, it is usual for three haplotypes to be formed (i.e. D′ = 1) and for the fourth only to form later and slowly by recombination events.

A linkage locus chr16q22.3-q23.1 identified by Tyynismaa et al. is very close to a suggestive linkage region identified by Bisceglia et al. [ 87, 98].

On the X chromosome, RPL10 locates very close upstream to the TKCR linkage region, but disease mapping by linkage analysis is often imprecise.

The study showed that some α-amylases are able to hydrolyze α-glucosidic linkages very close to the branch points in starch.

Likewise, average fitness (w) and neutral genetic diversity (H) are very close to their corresponding expectations, and linkage disequilibrium is always nonsignificantly different from zero.

This cis-element may be situated within or very close to the gene, as the linkage disequilibrium block where rs172378 lies is 11.9 kb long and includes the whole gene (3.1 kb) as well as up- and downstream regions.

The Chebyshev parallel motion is a three-bar linkage that gives a very close approximation to exact rectilinear motion.

An association between an SNP and the phenotype may arise if the SNP itself is the functional genetic variant, or if the SNP is very close to it (i.e., in linkage disequilibrium with the true causal allele).

The gene was mapped into the linkage group E03 at 89.6 cM very close to the 4CL gene (90.9 cM).