Our results shed light on the regulation of MSCs through directional ECM structures and demonstrate the versatility of these cell culture platforms for guiding the morphogenesis of tissue types with anisotropic structures.
Umbilical cord tissue-derived MSCs exhibit a neuronal phenotype [ 13– 16] and are potentially useful for the treatment of neurodegenerative diseases [ 17, 18], again showing the versatility of this cell source.
Thus, although several molecular processes are common to CR, CAS and ZYM adaptive responses, specific gene/proteins are required to cope with distinct cell wall alterations, showing the complexity and versatility of the cellular cell wall stress response network.
1 However, to further demonstrate the versatility of the eCPX cell surface display scaffold, and directly compare the relative performance with an aluminum binding peptide developed by phage, we genetically engineered the system to allow programmed display of peptide sequences, including Al-S1.
In other words, the versatility of the stem cells she discovered might be something created in the laboratory, not a natural property.
The encouraging results obtained with aptamers combined with their intrinsic properties and the versatility of the live cell-SELEX procedure have inspired us to employing this method to develop gastric cancer specific DNA aptamers.
Clearly, there remains a significant need for a recombinant protein expression platform that combines the versatility of mammalian cell culture and the cost-effectiveness of bacterial systems with several other attributes lacking in both technologies.
Efficient and reliable inducible expression systems can improve the versatility of plant cell cultures still further by restricting protein expression to the most productive growth phase and preventing exposure to proteases which reduce both the quantity and the quality of the product.
Extravascular macrodevices are designed as macrocapsules, planner membranes or hollow fibers, all of which have the advantages of encapsulating large number of cells and the versatility of cell retrieval from implantation site in case of post-operative complications.
