Sentence examples for versatile transcription factor from inspiring English sources
Sp3 is known to be a versatile transcription factor [53], [54], which either suppresses promoter activation by Sp1 or, at the opposite, cooperates with Sp1 on promoters.
The versatile transcription factor NF-κB is markedly increased in the RA synovium [ 12, 13].
As a versatile transcription factor, NF-κB has been reported to induce MMP2 and MMP9 expression to promote HCC metastasis (Li et al. 2011).
Selective binding is determined by interactions with more than 60 different cofactors, which turn SRF into a versatile transcription factor translating cell- and stimulus-specific signaling into selective target gene expression [ 1, 2].
It would appear to be in the best interest of the melanoma cells to rely on a versatile transcription factor that can supply as many gene products as necessary for its growth and survival.
The CCCTC-binding factor (CTCF), known as a versatile transcription factor and chromatin insulator and to be involved in X inactivation, has also been suggested to be a tumour suppressor on 16q.
CTCF is a highly conserved and ubiquitous transcription factor with versatile functions.
CCCTC binding protein (CTCF) is a highly conserved and ubiquitous transcription factor with versatile functions.
Here, we describe a straightforward and versatile work-flow for both transcription factor and histone mark ChIP-seq on low abundance cell populations isolated directly from the in vivo setting.
Here we utilized studies of Arabidopsis in parallel with heterologous expression of START domains in yeast to investigate the hypothesis that START domains are versatile ligand-binding motifs that can modulate transcription factor activity.
In summary, we described versatile expression vectors that provide a range of levels of expression of heterologous proteins in yeast, plasmids encoding a transcription factor substrate with a cleavable linker to accommodate various protease specificities, and methods for configuring complex multi-component protease activation pathways for high throughput chemical library screening.
