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Recent work has shown that tissue-specific miRNAs offer a versatile target that can be exploited to control the tropisms of gene expression vectors and of replication-competent viruses.
The proposed scheme may open a new QDs-based ERET system for highly sensitive detection of versatile target biomolecules, and has a good prospect for clinical diagnosis in the future.
By building a retractable probe incorporating a versatile target holder, and modifying the ion optics of a commercial mass spectrometer, we show that we can steer the macromolecular ion beam onto a target for imaging by means of transmission electron microscopy and atomic force microscopy.
This study also validates the ssrA gene as a suitable and versatile target for nucleic acid-based diagnostic tests for bacterial pathogens.
Given findings that GLO1 mitigates aging-associated endothelial dysfunction, which causes CVD in the long term, regulation of glycative stress may represent a versatile target for the prevention of vascular aging and CVD.
These observations, along with our finding that these responses can be detected within six months of infection and are common among HIV-infected individuals, suggest that this epitope is a versatile target for HIV-specific ADCC-mediating antibodies.
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Polymeric microparticles with covalently attached biotin are proposed as versatile targeting vehicles for drug delivery.
To combat this problem, we have developed a versatile targeting system using metabolically biotinylated adenoviral vectors bearing biotinylated fiber proteins.
The contradictory activities may correspond to variations among Cers in their carbon chain lengths, double bond numbers, subcellular distributions, and versatile targets.
Despite their central position in diverse signalling processes, the role of NHERF proteins as versatile targets for bacterial effector proteins has not been fully investigated.
The real-time PCR test developed in this study targets the bacterial ssrA gene which was previously shown to be a versatile diagnostic target for important food and clinical pathogens [ 18, 19].
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