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AAA+ proteins are ubiquitous mechanochemical ATPases that use energy from ATP hydrolysis to remodel their versatile substrates.
Mesoporous silica thin films and nanoparticles prepared by surfactant-templated sol gel techniques are versatile substrates that can be easily derivatized with active molecules to create functional materials.
These methanogens use versatile substrates and contain both acetotrophic and hydrogenotrophic pathways for methane production.
The high-throughput Ni-NTA Plate OGT Assay will facilitate discovery of potent OGT-specific inhibitors on versatile substrates and the characterization of new enzyme variants.
The most prevalent species appears to be Methanosarcina barkeri fusaro, which uses versatile substrates and contains both acetotrophic and hydrogenotrophic pathways for methane synthesis [ 62].
This reference species possesses a relatively thick cell wall (composed of acidic heteropolysaccharide) that forms a protective sheath, and it uses versatile substrates for methane synthesis, making it more adaptable to the environment as compared with its relatives.
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The functional diversity of RNA makes it an attractive and versatile substrate for programming sensing, information processing, computation, and control functions.
The racemate of poly l-lactide) and poly l-lactide) ando crystallize epoly d-lactide ≈165°C) on HMB, which apoly d-lactide very versalsoe substrate.
Printing on a versatile substrate provides a method to monitor the positioning of different molecules by using a pH-responsive boronate ester, allowing specific host-guest interactions on any surface.
Our crystal structures explain the extremely versatile substrate diversity of the enzyme and provide a first step towards the rational design of novel tetracycline derivatives to counter TetX-based resistance prior to emerging clinical observations.
As an example, tetrabromobisphenol A, a commonly used flame retardant, mimics E2 binding to SULT1E1, making use of the versatile substrate binding pocket and inhibiting the activity of the enzyme (119).
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