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For the proof of concept, microRNA-21 (miR-21) was selected as the model target to testify this strategy as a versatile assay platform.
Here, we develop a versatile assay for differential chemical inhibition of competing microbial strains, and use it to identify compounds that preferentially inhibit tetracycline-resistant relative to sensitive bacteria, thus "inverting" selection for resistance.
The utility of these versatile assay components and their application for screening strategies was validated for all ten human Caspases, a family of intracellular proteases involved in cell death and inflammation, including implementation of assays for high throughput screening (HTS) of chemical libraries and functional screening of cDNA libraries.
A simple and versatile assay for CTC capture and genomic or proteomic analysis is ISET.
Behaving as robust and versatile assay components, the phage particles are unconventional reagents for the immunoassay industry, and their biological nature can become a safety issue.
For rapid and initial analysis of the cell's response in terms of proliferation, apoptosis, and necrosis, our group has developed a simple and versatile assay based on microplate assays analyzing metabolic enzymes [ 67, 70].
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Its versatile microarray assay contains over 12,000 electrodes available for individual assay.
Moreover, the replacement of the enzyme by the less-expensive and non-polyphenol-forming hematin for this versatile colorimetric assay may provide convenient results, especially in flow-injection modes and analytical columns applications.
By contrast, the western blot is regarded as the most versatile homogeneous assay for quantifying signaling activities, in part due to the availability of specific antibodies.
The peptide-based nanosensor provides novel approaches to design versatile biosensor assays by LSPR for chemical molecules.
Here, we have developed a versatile cell-based assay system to monitor sLex biosynthesis using the GeneSwitch System.
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