Exact(2)
The comparitive genomics based approach using the concept of regulogic extrapolation as explained in [ 33] was carried out to retrieve orthologous regulatory relationships in S. mutans from experimentally verified relationships in B. subtilis.
Five out of eight regulatory-target relationships involving these four regulators were significantly enriched with ChIP-chip verified relationships (Table 1).
Similar(58)
To verify relationships from our gene list and the existing knowledge in the literature concerning genes and atherosclerosis, we used the automated literature mining tool, termed MedGene (hptt://hipseq.med.harvard.edu/MEDGENE/login.jsp), which summarizes and estimates the relative strength of all human gene disease relationships in Medline [10].
Additional alignments and reverse BLAST experiments were performed to verify relationships as appropriate.
Precision is important to researchers because an experiment to verify relationships identified in exploratory work can be expensive.
The algorithm was able to verify relationships known to exist in literature and also some previously unknown relationships including those with regulatory and signaling functions.
PFGE was performed according to a modified protocol based on Turabelidze et al. [ 27] to verify relationships of the PhP-subtypes.
However, multiple independent sources of information should be used to verify relationship status when available.
To verify relationship between miR-20b and HIF-1 α, VEGF expression, we also transfected miR-20b mimics and miR-20b inhibitor to HepG2 cells.
The Friedman test followed by the Dunn post-hoc test was utilized to compare the variables among conditions before and after surgery, and Spearman correlation analysis to verify relationship among RMSSD and pulmonary parameters.
By doing so, we could deduct necessary factors for each levels of innovation and empirically verified their relationships.
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