Five more InDel polymorphisms were identified during Sanger verification of the intervals in which CO events occurred, resulting in a total of 93,528 total polymorphisms.
This cutpoint was determined by standard clinical laboratory comparison methods and verification of the reference interval [ 26- 30].
DNA was fragmented by sonication (Branson Sonifier B-12: output control to microTip limit, 35 times at 5 s intervals); verification of the successful fragmentation in term of size and quantity was verified on 1 % agarose gels.
The aleatory component is integrated in the computation of fragility curves, whereas the epistemic component provides the confidence intervals; (c) computation of fragility curves with Monte Carlo method and verification of the validity of the log-normal assumption.
Thus, the diagnostic intervals are shorter than if we had used the date of histological verification of the diagnosis.
A verification of the accuracy of and, in consequence, updating of the RF and the RR in regular time intervals (i.e. every 5 years) is also a strategy to consider.
Independent verification of the data seemed imminent.
(c) Verification of the universal markers.
Verification of the hypothesis requires extensive laboratory tests.
There is no verification of the audit trail".
