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Ordinary H&E staining of the first and last section before the sections that were HPV genotyped enabled verification of whether the sections tested did indeed contain cancer tissue.
There are over 100 strains of HPV.
We found an unexpected HPV distribution with an abundance of HPV 52 and HPV 72 infections.
Using a condom can help prevent the transmission of HPV.
The same strains of HPV cause both cancers.
Table 1 Prevalence of HPV in different years.
Sekine, M. et al. Japanese Crisis of HPV Vaccination.
The HPV surrogate score was developed using a logistic regression model predicting HPV-positive status.The HPV surrogate score was predictive of HPV status (area under the curve [AUC] 0.73; accuracy of 70.4%).
HPV 33 and HPV 58 were present in 20% and 40%, respectively of HPV positive benign samples.
HPV 16 and HPV 18 normalized viral load is reported as the number of HPV genomes per 20 000 GAPDH copies.
Detection of HPV mRNA may improve specificity.
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