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A simple evaluation of plasma natriuretic peptide concentrations could help to discriminate patients with preeclampsia who have a condition of mild left ventricular overload.
The primary goal of this approach is to avoid potential heart failure associated with complications of congenital or valvular defects, such as ventricular overload.
In particular, patients with ARDS may develop right ventricular overload and acute cor pulmonale (ACP) [2 4].
This study was undertaken to evaluate ventricular performance and beta-adrenergic receptor signaling in a tricuspid regurgitation model of right ventricular overload.
CONCLUSIONS: Early right ventricular overload is associated with impaired right ventricular chamber contractility, dilation, and, importantly, a biventricular alteration of beta-adrenergic receptor signaling.
By means of the shell-subtraction model, right ventricular pressure-volume relationships were evaluated in normal and right ventricular overload states.
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It has mostly been described in hypertension [15] and diabetes [16], but it is also present in the ageing heart [22], in idiopathic dilated cardiomyopathy [23], and in left ventricular pressure-overload and volume-overload states induced by chronic aortic valve regurgitation and stenosis [24].
Beetz, N. et al. Ablation of biglycan attenuates cardiac hypertrophy and fibrosis after left ventricular pressure overload.
Crozatier, B. & Ventura-Clapier, R. Inhibition of hypertrophy, per se, may not be a good therapeutic strategy in ventricular pressure overload: other approaches could be more beneficial.
Comparison of twitch force and calcium handling in papillary muscles from right ventricular pressure overload hypertrophy in weanling and juvenile ferrets.
The complete ablation of ERRα leads to defects in ATP production and transport in the mitochondria of the heart, which develops signatures of heart failure after ventricular pressure overload compared with wild-type mice28,58.
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