International variation in aspects of the delivery of mechanical ventilation such as preferred ventilator mode, use of non-invasive ventilation (NIV), and adoption of protocols for weaning has been noted previously [ 12, 13].
PROP; Proportional ventilator mode (either Proportional Assist Ventilation or Neurally Adjusted Ventilator Assist).
In addition, the ventilator mode and level of ventilation that a patient is on before calculation of a PV curve can affect the shape of the curve [ 9].
Median mechanical ventilator mode was 3 (controlled ventilation) (interquartile range 2 3) before PT and 2 (spontaneous ventilation) (interquartile range 1 3) after PT (p < 0.001; Figure 3).> -wrap-foot> Fentanyl, midazolam, and propofol presented as mean (standard deviation) of the three last days before PT and the three days after PT.
The other trial [46] compared low-stretch ventilation guided by peak or alternatively plateau airway pressures, depending on the ventilator mode utilized, to low tidal volume ventilation.
Proportional assist ventilation (PAV), described by Younes [1], was the first ventilator mode that introduced the concept of 'patient-driven' ventilation: a patient's effort could influence not only the timing but also the magnitude of the ventilator assistance.
Exercise significantly increased minute ventilation (VE) with no significant effect of the ventilator mode on respiratory pattern and SpO2 (Table 2).
The ventilator mode was changed to intermittent positive-pressure ventilation and autonomic nervous system derangement was apparent, with moderate hypotension (mean arterial pressure 70 mmHg), and groin temperature remained above 38°C.
Within the context of ventilator-induced lung injury and lung protective strategies, high-frequency ventilation could be considered to be the optimal protective ventilator mode.
After 1 hour of anaesthesia with 1.0 MAC the ventilator mode was switched from SIMV VC+ (totally controlled ventilation, passive patient, with a tidal volume of 8 ml/IBW) to proportional assist ventilation with 50% support (active patient).
Prior to further randomised trials being undertaken, it is essential that the optimum method of applying each ventilator mode is identified and it is clearly understood whether differences in ventilator/oscillator performance influence outcome.
