Incidence densities (episodes per 1,000 days ICU stay or device use for mechanical ventilation, catheters, urinary catheters) were calculated and compared to those of non-CCI patients.
All of the patients were admitted to an intensive care unit (ICU), and they received standard intensive care and monitoring, including mechanical ventilation, arterial catheters, central venous catheters, urinary catheters, and rectal temperature measurements.
Instrumentation was defined as receipt of Foley catheterization, chest tube, Swan-Ganz catheterization, mechanical ventilation, dialysis catheter, central line, arterial line, peripherally inserted central catheter, permanent central venous catheter, balloon pump, or intraabdominal or other surgery.
The data on duration of mechanical ventilation, intravascular catheter complications or hospital stay were not suitable for meta-analysis.
The E.a. colonization/infection was not significantly associated with patient's median age, mortality rate, antiobiotherapy prior to ICU admission, mechanical ventilation, urinary catheter and surgical drain.
Sepsis was more severe among excluded patients (higher rates of mechanical ventilation, indwelling catheters, septic shock and organ failure).
Other risk factors more commonly found in the solid tumours group were ileus, use of anaerobicides, requirement of invasive mechanical ventilation, urinary catheters, and admission to the intensive care unit.
SAPS II score, prior surgery or antibiotics, impaired immunity, trauma, and infection at entry, (ii) During ICU stay, exposure to ventilation, central catheters and a number of other devices and treatments were recorded on a daily basis, (iii) If a PN or BSI occurred, diagnostic criteria were registered in detail, including microbiological evidence.
In addition, the following data were collected during ICU stay: number of sites colonized with fungi, antibiotic treatment, mechanical ventilation, central venous catheter, arterial catheter, dialysis, duration of ICU stay, duration of antifungal treatment, parental nutrition, and ICU mortality.
