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LEE is defined as the fraction of emitted power out of the LED structure to the total emitted power, which is determined by the ratio of Poynting vectors integrated over extraction surfaces to total integrated Poynting vectors[18].
As expected, all RV vectors showed a preference for integration around TSSs, while LV vectors integrated preferentially within genes, as compared to the control sequence set (Figure 1).
The ϕC31 integrating vectors integrated with higher efficiency and were more stable than the pSAM2-derived integration vectors and are now widely adopted by researchers in Streptomyces genetics.
In F. heterosporum, linearized vectors integrated ectopically and intact.
According to our previous study, the copy number of the expression vectors integrated into the genome was assumed to be one (Ishida et al. 2000).
This approach is based on the ability of therapeutic lentiviral vectors integrated in mucosal epithelial stem cells to induce virus-specific cellular immune responses at mucosal sites of viral entry.
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Additionally, retroviral vectors integrate into the host cell genome, incurring the risk of gene disruption and cellular transformation.
Vector-based shRNA libraries are able to provide long-term and stable gene silencing because the vectors integrate into genomic DNA and are thus replicated.
This concept defines the principal, cumulative vectors, integrating the tissue architecture (ie, form) and net forces developed (ie, function) within the ventricular mass.
Both vectors integrate into the same locus (AOX1), and therefore by using Δku70, which prevents off-target integration, a higher proportion of clones with the correct integration should be observed (Naatsaari et al. 2014).
MLV and MLV-based vectors integrate near strong enhancers, active promoters, and transcription start sites (TSS) through specific interaction of MLV integrase (IN) with the bromodomain and extra-terminal (BET) family of proteins, accounting for insertional mutagenesis.
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