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The pSilencer4.1-CMV vector and pcDNA3.1 vector were obtained from Ambion.

The Cre expression vector and LoxP vector were obtained from E. Bouhassira[10].

Src cDNAs (pUSE Src wild type, pUSE Src kinase mutant, and empty vector) were obtained from Upstate Biotechnology, Inc. (Lake Placid, NY).

The PSA-enhancer-Luc reporter, containing a 6.1 kb DNA fragment corresponding to the human PSA enhance plus promoter [36], and the pOZ-N vector were obtained from Dr. Jiemin Wong (Baylor College of Medicine, Houston, TX).

Lentiviral shRNA in the pLKO.1-puromycin vector were obtained from the Sigma Mission shRNA library.

The Cre expression vector and LoxP vector were obtained from E. Bouhassira [ 3].

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Finally, the digitized measurement vector is obtained.

Finally, the adaptive weight vector is obtained.

Hence, the time support vector is obtained as (15).

The pTurboGFP-PRL expression vector was obtained from Evrogen (Moscow, Russia).

Thus, a 256-dimensional feature vector is obtained.

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