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Concentrated PB-based vector was administered to the barrier gel and allowed to be released to the buffer.
In in vivo rescue studies, vector was administered before or after wt-AAV2 and Ad2HR405 infection, and the shedding of AAV-CFTR was examined.
The AAV-Stop-CB1 vector was administered to the hippocampus of adult NEX-Cre mice to achieve conditional CB1 overexpression in hippocampal glutamatergic cells (AAV-Glu-CB1 mice).
To each submandibular gland 50 µl vector solution, containing 1×1011 vector (ICAM-1/Fc or control vector LacZ) particles plus 1×109 luciferase reporter vector, was administered by retrograde ductal instillation using a thin cannula (Intermedic PE10, Clay Adams, Parsippany, NJ), as previously described [7].
Vector was administered as a bolus infusion via a saphenous vein as previously described.
Adenoviral vector was administered in a volume of 100 μL to 8 × 8 × 8 mm tumours.
Similar(43)
We show that hepatocarcinoma is a permissive tumor for adenoviral infection and that the nontumoral cirrhotic liver is spared from transduction when the vector is administered by intratumoral injection.
In order to test the safety and biological activity of AAV-CFTR, single doses of AAV-CFTR vector were administered by fiberoptic bronchoscopy to the posterior basal segment of the right lower lobe (RLL) of the lungs of 10 rhesus macaques with four matched vehicle-treated controls.
When GP42 vectors were administered (i.n). to mice, minimal weight loss was observed.
Vectors were administered intravenously, and DNA was recovered from lung tissue after 8 days.
Adenoviral vectors were administered 14 d after tumor cell implantation when tumor volume was ~100 mm.
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