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Retroviral vectors are commonly employed for long-term transgene expression via integrating vector technology.
By lentiviral vector technology, we achieved local or systemic delivery of decoy Met in mice.
Recent developments in extrachromosomal vector technology have offered new ways of designing safer, physiologically regulated vectors for gene therapy.
Advances in hematopoietic stem cell isolation and ex vivo manipulation has kept pace with improvements in retroviral vector technology to make hematopoietic stem cell transduction a distinct reality.
Progresses have been made in vector technology and design allowing for successful preclinical studies in skin gene therapy trials using different approaches.
Combined transgenic (i.e., germline modifications) and viral vector technology will also be very powerful in allowing the genetic modification of selected neuronal populations in adult animals.
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Expression vector engineering technology is one of the most convenient and timely method for cell line development to meet the rising demand of novel production cell line with high productivity.
Recent advancements in viral-vectored malaria vaccine development and emerging vector technologies were presented and discussed.
This chapter includes a brief description of available viral vector technologies and their contribution to vaccine design, using human immunodeficiency virus vaccine development as a case study.
Thereafter, analyses using human recombinant and lentiviral vector technologies were conducted to further dissect and elucidate a molecular mechanism that regulates hair growth and development, particularly in controlling the shape of the hair shaft.
This allows researchers to employ advanced vector technologies, initially developed in the gene therapy field, also for several types of RNA therapy.
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