Here, r is a binary indicator vector representing the reliability of observed data.
Owing to the inherent variability of RNAi feeding vector experiments, the reliability and reproducibility of our RNAi results was confirmed by comparing the observed behavioral phenotypes to previously published reports for the same RNAi clone, described in detail in ref. 18.
Although we are not interested to the exact value of the motion vectors, but only to distinguish between null and non-null vectors, the low reliability of their estimation has to be taken into proper account.
Among different possible choices, a simple -yet sensible- one is the linear cost index: (6) J = α · ε 1 + β · μ 1 with α≥0 and β≥0, which are row vectors of measurement reliability coefficients.
Moreover, motion vectors with the worst reliability have been corrected by vector median filter.
For calculating Agent Score (AS), we collected the agent phenotype similarity scores from the study of van Driel et al[ 31 ], in which the similarity score between two phenotypes is determined by the cosine of their feature vector angle, and the reliability of the score has also been tested [ 31].
This paper examines the potential of relevance vector machine (RVM) for slope reliability by using first order second moment method (FOSM).
According to the root mean square error (RMSE), correlation coefficient and average absolute relative deviation, the suggested support vector machine approach has acceptable reliability, integrity and robustness draw an analogy with the artificial neural network model and conventional methods.
When these assumptions are verified, deviations from the model are either due to the fact that some interest points are missed (e.g., because a part of body is very similar to the underlying background) or due to the limited reliability of motion vector estimation, that may cause some static points to be considered as moving.
Therefore, to avoid quality degradation of the side information due to untrustworthy predictors, all obtained motion vectors are subjected to a reliability screening.
