Sentence examples for vector modifications from inspiring English sources

For instance, they've doubled the speed of simple division, and added optimizations for vector modifications.

However, limited efficacy in clinical trials using Ad-based agents has clearly exposed the need for vector modifications designed to provide target cell-specific gene delivery and expression, thereby improving efficacy and safety.

The major coat protein, hexon, from a chimpanzee adenovirus (AdC68) is of interest as a target for vaccine vector modification.

Each of these regions is flanked by a restriction site that allows for easy vector modification, including removal of the signal sequence without perturbation of the reading frame.

We have demonstrated by the use of Isothermal Titration Calorimetry (ITC) that this vector modification resulted in activity preserved for a higher period.

Exploiting intracellular differences between normal and cancer cells for gene delivery vector design offers a new paradigm to achieve transfection selectivity based on intracellular differences rather than conventional approaches involving vector modification using specific ligands for targeted delivery.

Since no nucleic acid production or protein expression is required during the actual vector modification, procedure times can be kept brief and modifying molecules are not limited to factors naturally produced by cells.

Addition of stuffer DNA and vector capsid modification are some of the other aspects that need consideration during the production of these vectors.

Delivery of the oligonucleotides, choice of vector, chemical modification to stabilize against nucleases and avoidance of side effects (e.g. stimulation of interferons) are major challenges.

With these features, HACs are expected to be promising vectors for modifications of a variety of cell types.

Other hPLP1-lacZ partial deletion constructs were generated via intermediary shuttle vectors whose modifications were ultimately incorporated in the background of 2.7hPLPZ.