Western blot analysis shows that 25 ug of Cx43 expression vector was sufficient to increase Cx43 in SW480 cells compared to control or empty vector.
Introduction of mIGF-1 somatically using an Adeno-Associated-Viral (AAV) vector was sufficient to rejuvenate the leg muscles of 27 month old mice, which exhibited the same mechanical force as legs of younger mice, and did not develop the pathological characteristics of senescent muscle [ 20].
A single transfection of episomal vectors is sufficient for the derivation of human iPSCs.
Our studies with human CB CD34+ cells demonstrate that the mere transduction of these cells with BCR/ABL vectors is sufficient to inhibit the formation of FANCD2 foci, either in untreated or in MMC-treated cells (Figure 2).
Nevertheless, in the following sections, we show that 5 10 training sentences alone, which still result in several thousands of spectral feature vectors, are sufficient for training a GB conversion.
Taken together, these results demonstrated that a single immunization with nonintegrative lentiviral vectors was sufficient to elicit a humoral specific immune response with a strength comparable to that obtained with integrative vectors, above a threshold dose of particles.
Our data indicate for the first time that local delivery of HO-1 transgene by means of adenoviral vectors was sufficient to improve healing of excisional wounds in diabetic db/db mice, despite a low transduction efficacy.
