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We developed an HSV as an exemplar gene delivery vector for inducing biomarker secretion selectively from tumors.
Here, we studied the potential of our MVTT as a vaccine vector for inducing Nabs.
While they are applied to imaging, microbubbles also can be used as a nonviral vector for inducing stem cell homing [ 47].
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In 2004, a Phase IIb trial with Merck's MRKAd5, which is a trivalent vaccine including gag, pol, and nef genes in an adenovirus 5 vector, is designed for inducing cytotoxic T cell responses [ 9, 10].
Recently, a novel method for inducing vector space models was introduced by Mikolov et al. [ 42], stemming from the research in deep learning and neural network language models.
Adenoviruses are potent vectors for inducing and boosting cellular immunity to encoded recombinant antigens.
In conclusion, our replication-competent vaccinia vector MVTT is superior to MVA for inducing high levels of neutralizing antibody via mucosal vaccination.
Furthermore, several advantages of shRNA expression vectors mean that this approach is very suitable for inducing gene silencing.
Alpharetroviral self-inactivating vectors (ARV) have several advantages compared to other vector platforms, including a more random genomic integration pattern and reduced likelihood for inducing aberrant splicing of integrated proviruses.
Heterologous prime-boost using vector-based gene delivery of vaccine antigens is a potent immunization strategy for inducing both antibody and T-cell responses.
A number of studies have shown that irradiated L3 (L3ir) are more effective for inducing immunity to infection than L3 freshly isolated from vectors (L3i) [ 9- 11].
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