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Three weeks after injection of 5 × 106 ST4/pIKT-shPlk, PLK1 transcript levels in tumors were 62.5 ± 18.6% lower than the vector control group (P = 0.015).
(C and D) Representative histograms and normalized CXCR5 and Bcl6 expression (the mean MFI of the vector control group set as 1) on OT-II T cells transduced with the control or an ITK-overexpressing vector 24 h post immunization.
The vector control group had an average of 0.6% metastasis area, whereas the EGR1 group averaged 0.31% metastasis area (Figure 7C).
For each batch of oocytes, individual GIRK currents from the isoform-expressing group were normalized as a percentage of the average current of the vector control group.
The vector control group had an average of 51.2 cells, whereas the EGR1 group averaged only 18.7 cells (Figure 7A, B).
CMV signal was higher in the spine tissues of G3 treated animals than those of the vector control group (p<0.05) (Fig. 9b).
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The challenged, unchallenged and vector control groups were designed.
All mice immunized with RASTyV expressing pspA were significantly protected compared with BSG and empty vector control groups (P<0.01) (Fig. 10).
Study cohorts consisted of 10 female BALB/c mice for the HA alone, HA+NP, and HA+NP+M2 groups, and 5 animals for the NP alone and vector control groups.
For miR-200c target PDCD10 verification, the ratios of firefly/renilla in dual luciferase assaywere similar between reverse, deletion and empty vector control groups (13.99 ± 2.50, 13.37 ± 1.73 and 12.36 ± 1.44), whereas the relative luciferase activity (6.40 ± 0.73) was significantly lower in the test group (P < 0.05) (Fig. 4b and c).
The number of ki67-positive cells inversely correlated with the level of TGFBI expression; the more ki67-positive cells observed in the vector control groups, the stronger the evidence that TGFBI diminishes the ability of cells to proliferate and therefore inhibits tumorigenicity in vivo.
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