Even in this regard, the Farrellys have been left behind by such directors as Wes Anderson and Jared Hess, whose comic imaginings may not be as mechanically pure and efficient as those of the Farrellys but whose over-all sense of cinematic style is vastly more comprehensive and complex, and whose carefully composed humor — as well as their elaborate world view — is integral to that style.
However, the CCKR map constitutes a vastly more comprehensive and integrated model, providing detailed signaling reactions linking the receptors CCK1R and CCK2R all the way to regulated genes and cellular responses.
Yet, when we ask ourselves, as many have been doing in this anniversary year, what do we know now that Darwin did not know?, the answer includes a vastly more detailed and comprehensive knowledge of the fossil record of the history of life.
We have vastly more powerful tools than ever before, we have comprehensive methods of collecting data to inform our work, and national governments are leading the charge, leveraging external assistance to dramatically reduce malaria illnesses and deaths.
In fact, the Director of the US National Cancer Institute issued a challenge to the scientific community in 1999 (NCI, 1999) to 'harness the power of comprehensive molecular analysis technologies to make the classification of tumours vastly more informative.
In January 1999, the U.S. National Cancer Institute (NCI) issued a challenge to the scientific community "to harness the power of comprehensive molecular analysis technologies to make the classification of tumors vastly more informative.
In 1999, the director of the National Cancer Institute challenged 'the scientific community to harness the power of comprehensive molecular analysis technologies to make the classification of tumours vastly more informative.' This challenge aimed to change 'the basis of tumour classification from morphological to molecular characteristics' (NIH Guide, 2008).
The rapid identification of geochemical trends vastly improved our selection of samples for shipboard and shore-based analysis, permitted a more comprehensive interpretation of our Expedition results, and provided key decision-making information for drilling operations.
With the current vastly improved computing power and storage capacity, we advocate using genome-wide gene profiles to provide a more comprehensive genomic analysis comprising a portfolio of current gene expression profiles that includes CMTC, complete oncogenic pathway analyses and the potential for future analyses if pathway gene signatures are further refined.
This is vastly more important".
The task now is vastly more complicated.
