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The repeatability of VAst (standard alveolar volume obtained following the ERS-ATS recommendations) and of VAq (alveolar volume measured according to the method of subdividing the whole expirate into quintiles) was tested both in healthy individuals and in patients with COPD and has been reported in Table 2.
The mean values of VAst (standard alveolar volume obtained following the ERS-ATS recommendations) and VAq (alveolar volume measured according to the method of subdividing the whole expirate into quintiles) of two consecutive tests were compared by the paired Student t-test to assess their statistical differences.
This analysis showed only a slight increase of VAst (standard alveolar volume obtained following the ATS-ERS recommendations) when it was associated with a higher flow, not exhibited by the calculated VAq (alveolar volume measured according to the method of subdividing the whole expirate into quintiles).
This result indicates that VAst (standard alveolar volume obtained following the ATS-ERS recommendations) is more sensitive to the different profile of emptying of alveoli when compared to the method of quintiles, which always takes into account its standardization for the whole expired volume of the subject (which is 20% of the whole expirate).
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com