"vast setback" is correct and can be used in written English.
It is typically used in the context of encountering a large obstacle or hindrance which makes it difficult to achieve a desired outcome. For example: "The company's plans for expansion have been met with a vast setback due to the pandemic."
Many of us know of the vast challenges and setbacks from poor leadership to bad decisions to underdeveloped infrastructure.
Both are cynical idealists, having been conditioned by decades of combat, going back to Bill's first campaign, an unsuccessful House race in 1974, to see enemies and vast conspiracies behind every setback.
The firm's efforts to elbow into first-party hardware have therefore received a massive setback, writing down the vast majority of the purchase price of its phone business.
World War II caused a drastic setback to the breed, with the vast majority of breeding stock destroyed because of the hardship.
But they certainly did not provoke any vast crisis of conscience or even, apparently, a serious setback for the Republican White House's much vaunted "Catholic strategy".
Despite the setback, the League Two side had the vast majority of possession and chances before the break, with Morsy and Evatt both guilty of wasting very presentable opportunities.
Both writers leave readers with the impression that vast, immutable economic upheavals are the cause of these setbacks for men.
And it delivers a setback to the Revolutionary Guards (IRGC), the powerful security force which controls a vast industrial empire in Iran.
We have vast untapped potential in our fertile agricultural lands, particularly in the north and east -- previously setback through terror for three decades and now active once again.
The vast majority of graduate job application forms ask a referee to comment on "reaction to setbacks" - because potential employers want to know that potential employees are prepared to learn, take criticism and move forward.
