The country has developed a vast response network in which Dr. Hiss plays a unique role.
We don't want to be dragged into a vast response there, where we destroy 10 or 15 houses, and there are civilian casualties, and then they call for international forces to be sent to Jerusalem".
Such a vast response may be due not only to damage to DNA but also damage to proteins, RNA, and lipids.
Given this vast transcriptional response to damaging agents like MMS and the knowledge that, in addition to DNA, these agents can also damage proteins, RNA and lipids, we set out to identify the transcriptional response specifically caused by damage to DNA.
Algorithm genetic can contain a large vast of responses and find the best of them by receiving feedbacks from problems.
"But for the vast majority, the response will be really good".
In the instance of the Boston story, the scope of the crime, the number of victims and the fact that it smacked of terror on American shores provoked a vast law enforcement response at the federal and local level.
Rather than having a video recording network, we would have a vast real-time response system, able to alert emergency services to potential accidents before they happen, or stop a crime in progress.
These challenges may also be compounded by the rapid erythrocyte turnover and anemia in SCD, the heterogeneous multi-organ complications and the numerous genetic polymorphisms affecting disease severity, predisposition to specific phenotypes, the vast variation in response to HU treatment and the overall clinical course of the disease [60].
Upon ER stress, both the transcription factor XBP1s, produced as the consequence of a non-conventional mRNA splicing reaction initiated by IRE1, and the transcription factor ATF6, produced by proteolysis and release from the ER membrane, collaborate with ATF4 to induce the vast UPR transcriptional response.
While the vast majority of responses to our questions yielded consistent answers, we did find 34 respondents who gave inconsistent responses on questions about the time frame they would most like to know (e.g., choosing 5 days as the "most important" time frame, but strongly disagreeing with the idea of considering a patient's risk of clinical deterioration while in the hospital).
