Sentence examples for vast difficulty in from inspiring English sources

But the 250,000 Palestinians who live there have vast difficulty in getting permits to build houses and when they build illegally they are targets for demolition orders.

The existence of such complications explains the vast difficulties encountered in clinical trials with novel compounds.

The international team had to overcome vast difficulties to get their results.

The treacherous road conditions and the difficulty in removing vast amounts of snow also lead to numerous school closings.

Without the economies of scale that the NYSE reaps, its overheads would soon turn it into a decidedly high-cost provider.Even rivals to the NYSE acknowledge that only a very few shares (perhaps 50-100 firms) are truly liquid, meaning that volumes are so vast that there is never any difficulty in trading.

However, at present, extensive use of this gene delivery system in in vivo settings is hampered by the difficulty in obtaining the vast amounts of vector particles needed for large animal experiments and the limited understanding of the physiological effects caused by the interaction(s) between vector capsids and, for instance, the innate immune system.

Ensuing discussion revolved around how their continued difficulty in integrating the vast information provided by the RAI-MH into their clinical practice likely contributed to the absence of change in communication patterns with community staff.

Doing so would have complicated the terrorists' calculation of the difficulty in succeeding in a vast, open society that, in effect, was unprotected on Sept. 11.

P-gp has a vast endogenous and exogenous substrate profile that renders difficulty in drug delivery across the BBB.

As with the vast majority of human fMRI studies, however, there is difficulty in relating these results to mirror neurons, in that they only employ an action observation condition and have no action execution condition.

The quest for simple cis regulatory codes is therefore important but also challenging, given the difficulty in even identifying cis regulatory elements within the vast non-coding sequences of DNA [6].