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But some substances are so potent that a minute quantity can bring about vast changes in the body.
At Yin Yu Tang, by contrast, the basic layout lasted two centuries, despite vast changes in the family's circumstances.
Humanity has gone through vast changes in the 150 years since photography was first used on the battlefield.
Overall, his message seemed to be that technology and the developers to whom he was speaking have the ability to make vast changes in the world.
What the commuting public will probably remember from Mr. Conway's years as chairman are the two vast changes in the way people paid for transit that took place under his watch.
Lost in all this partisan wrangling was the fact that American diplomacy has already undergone vast changes in the past few decades and is now so heavily encumbered by fortresslike embassies, body armor and motorcades that it is almost unrecognizable.
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To speak of a gender "gulf" in America in terms of who voted for Gore, who drives an S.U.V. and how many sexual partners one has is to belittle the vast changes in this country in the past 30 years.
The vast change in the Baltimore Orioles over the past couple of years can be measured by their success against the Boston Red Sox, even when their AL East rivals send Jon Lester to the mound.
Singapore Airlines introduced the interior of its first A380 superjumbo jet in an elaborate ceremony here today, bringing an end to a decade's anticipation of what the airline has always said would mark a vast change in the level of quality and comfort in long-haul air travel.
"In recent years, we've seen a vast change in the number of Asian and black actors who are representing the multicultural nature of our business, and I think a play like Miss Saigon is vital because it plays to the strengths of every side of the acting spectrum".
But also, among other people, Harold Bloom who told me recently that "there is a vast change in the cultural climate, which has devalued the very difficult act of solitary deep reading".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com