We chose to target caspase-3, an executioner caspase, and caspase-8, an initiator caspase, based on the vast amount of information linking their functions to diseases.
These resources offer a vast amount of information about the functions and interactions in the whole genome-wide system.
These advances in rhizobial genetics have generated a vast amount of information about gene function and regulation; however, the advances have simultaneously raised the need for development of novel molecular tools which make use of the results of these functional analyses.
Compared to the vast amount of data describing the structures, functions and localisations of Dictyostelium myosins [ 27, 28], there are so far only a few investigations of Dictyostelium kinesins.
First, these approaches do not incorporate the vast amount of information already available on the functions of the genes.
Forward and reverse genetics, inducible expression systems and, more recently, large scale methods, such as chromatin immunoprecipitation followed by array hybridization or massive parallel sequencing, have provided a vast amount of information regarding target genes and functions of many Arabidopsis TFs.
There is a vast amount of evidence for hormone-dependent modification of function and behavior during the menstrual cycle, but little is known about associated structural alterations of the brain [1], [2], [3], [4], [5].
Despite the vast amount of studies done deciphering the role of the Mediator complex, few studies have demonstrated tissue specific functions for transcriptional regulation in mammals.
To use this vast amount of genomic information now available, genes related to specific traits need to be identified and their exact functions determined.
